| Date | Location | Result | |
| 02/26/22 | Manning & Napier Gym - Pittsford, N.Y. | St. John Fisher 83, Nazareth 52 | Box score |
| 02/25/22 | Manning & Napier Gym - Pittsford, N.Y. | Nazareth 70, Hartwick 68 | Box score |
| 02/19/22 | Nielsen Cnter - Houghton, N.Y. | Nazareth 58, Houghton 43 | Box score |
| 02/18/22 | Galanis Family Arena - Alfred, N.Y. | Alfred 59, Nazareth 56 | Box score |
| 02/12/22 | Kidera Gymnasium - Nazareth College | Nazareth 67, Keuka 29 | Box score |
| 02/11/22 | Clark Gymnasium - Utica, N.Y. | Nazareth 67, Utica 62 | Box score |
| 02/08/22 | Kidera Gymnasium - Nazareth College | St. John Fisher 64, Nazareth 42 | Box score |
| 02/06/22 | Kidera Gymnasium - Nazareth College | Hartwick 86, Nazareth 72 | Box score |
| 02/05/22 | Kidera Gymnasium - Nazareth College | Nazareth 65, Russell Sage 40 | Box score |
| 02/01/22 | Kidera Gymnasium - Nazareth College | Nazareth 73, Elmira 51 | Box score |
| 01/29/22 | Bobby Wanzer Court - Pittsford, N.Y. | St. John Fisher 78, Nazareth 73 | Box score |
| 01/28/22 | Kidera Gymnasium - Nazareth College | Nazareth 74, Alfred 57 | Box score |
| 01/18/22 | JMW Rec Center - Keuka Park, N.Y. | Nazareth 71, Keuka 35 | Box score |
| 01/15/22 | Kidera Gymnasium - Nazareth College | Nazareth 75, Utica 51 | Box score |
| 01/14/22 | Speidel Gymnasium - Elmira, N.Y. | Nazareth 72, Elmira 57 | Box score |
| 01/08/22 | Kahl Gymnasium - Albany, N.Y. | Nazareth 70, Russell Sage 47 | Box score |
| 01/07/22 | Lambros Arena - Oneonta, N.Y. | Hartwick 66, Nazareth 62 | Box score |
| 01/04/22 | Kidera Gymnasium - Nazareth College | Nazareth 88, Houghton 53 | Box score |
| 12/30/21 | Kidera Gymnasium - Nazareth College | Nazareth 86, Alfred State 62 | Box score |
| 12/08/21 | Dods Hall - Fredonia, N.Y. | Nazareth 51, Fredonia 50 | Box score |
| 12/05/21 | The Doghouse - New York, N.Y. | Nazareth 77, John Jay 52 | Box score |
| 12/01/21 | Kidera Gymnasium - Nazareth College | Nazareth 68, Cazenovia 27 | Box score |
| 11/20/21 | St. John Fisher - Pittsford, N.Y. | RIT 72, Nazareth 61 | Box score |
| 11/18/21 | St. John Fisher - Pittsford, N.Y. | Rochester (NY) 80, Nazareth 54 | Box score |
| 11/14/21 | Harold Alfond Forum - Biddeford, Maine | Colby 59, Nazareth 53 | Box score |
| 11/13/21 | Harold Alfond Forum - Biddeford, Maine | Bowdoin 65, Nazareth 44 | Box score |
| 11/09/21 | Kidera Gymnasium - Nazareth College | Nazareth 77, Medaille 57 | Box score |