| Date | Location | Result | |
| 05/07/22 | Pittsford, N.Y. | St. John Fisher 30, Nazareth 11 | Box score |
| 05/04/22 | Nazareth College | Nazareth 27, Alfred 3 | Box score |
| 04/30/22 | Nazareth College | Nazareth 30, Utica 11 | Box score |
| 04/24/22 | Albany, N.Y. | Nazareth 28, Russell Sage 11 | Box score |
| 04/20/22 | Keuka Park, N.Y. | Nazareth 28, Keuka 3 | Box score |
| 04/13/22 | Nazareth College | Nazareth 22, Alfred 8 | Box score |
| 04/08/22 | Oneonta, N.Y. | Nazareth 18, Hartwick 12 | Box score |
| 04/05/22 | Cortland, N.Y. | Cortland 17, Nazareth 9 | Box score |
| 04/02/22 | Nazareth College | St. John Fisher 20, Nazareth 14 | Box score |
| 03/23/22 | Ithaca, N.Y. | Ithaca 15, Nazareth 14 | Box score |
| 03/19/22 | Tampa, Fla. | Nazareth 22, Keene State 8 | Box score |
| 03/17/22 | Tampa, Fla. | Nazareth 22, Western New England 15 | Box score |
| 03/11/22 | Nazareth College | St. Lawrence 16, Nazareth 7 | Box score |
| 03/08/22 | Nazareth College | Nazareth 17, Brockport 10 | Box score |
| 03/05/22 | Potsdam, N.Y. | Clarkson 19, Nazareth 15 | Box score |
| 03/02/22 | Nazareth College | RIT 25, Nazareth 9 | Box score |
| 02/19/22 | Springfield, Mass. | Springfield 18, Nazareth 14 | Box score |