| Date | Location | Result | |
| 03/05/22 | Kidera Gymnasium - Nazareth College | UMass Dartmouth 78, Nazareth 68 | Box score |
| 03/04/22 | Kidera Gymnasium - Nazareth College | Nazareth 78, Westfield St. 71 | Box score |
| 02/26/22 | Clark Gymnasium - Utica, N.Y. | Nazareth 54, Utica 53 | Box score |
| 02/25/22 | Clark Gymnasium - Utica, N.Y. | Nazareth 80, St. John Fisher 71 | Box score |
| 02/19/22 | Nielsen Center - Houghton, N.Y. | Nazareth 92, Houghton 65 | Box score |
| 02/18/22 | Galanis Family Arena - Alfred, N.Y. | Alfred 69, Nazareth 55 | Box score |
| 02/12/22 | Kidera Gymnasium - Nazareth College | Nazareth 72, Keuka 57 | Box score |
| 02/11/22 | Clark Gymnasium - Utica, N.Y. | Utica 82, Nazareth 67 | Box score |
| 02/08/22 | Kidera Gymnasium - Nazareth College | St. John Fisher 87, Nazareth 80 | Box score |
| 02/06/22 | Kidera Gymnasium - Nazareth College | Nazareth 80, Hartwick 66 | Box score |
| 02/05/22 | Kidera Gymnasium - Nazareth College | Nazareth 93, Russell Sage 72 | Box score |
| 02/01/22 | Kidera Gymnasium - Nazareth College | Nazareth 81, Elmira 71 | Box score |
| 01/29/22 | Bobby Wanzer Court - Pittsford, N.Y. | Nazareth 77, St. John Fisher 71 | Box score |
| 01/28/22 | Kidera Gymnasium - Nazareth College | Nazareth 75, Alfred 66 | Box score |
| 01/18/22 | JMW Rec Center - Keuka Park, N.Y. | Nazareth 108, Keuka 71 | Box score |
| 01/15/22 | Kidera Gymnasium - Nazareth College | Nazareth 79, Utica 39 | Box score |
| 01/14/22 | Speidel Gymnasium - Elmira, N.Y. | Nazareth 70, Elmira 60 | Box score |
| 01/08/22 | Kahl Gymnasium - Albany, N.Y. | Nazareth 94, Russell Sage 63 | Box score |
| 01/07/22 | Lambros Arena - Oneonta, N.Y. | Nazareth 81, Hartwick 44 | Box score |
| 01/04/22 | Kidera Gymnasium - Nazareth College | Nazareth 74, Houghton 50 | Box score |
| 12/30/21 | Welch College- Gallatin, Tenn. | Nazareth 72, Carroll 58 | Box score |
| 12/29/21 | Welch College - Gallatin, Tenn. | Nazareth 78, Edgewood 72 | Box score |
| 12/07/21 | SUNY Poly - Utica, N.Y. | Nazareth 79, SUNY Poly 78 | Box score |
| 11/23/21 | Max Ziel Gymnasium - Oswego, N.Y. | Nazareth 67, Oswego 65 | Box score |
| 11/20/21 | Kidera Gymnasium - Nazareth College | Nazareth 90, RIT 77 | Box score |
| 11/18/21 | Kidera Gymnasium - Nazareth College | Nazareth 81, Rochester 73 | Box score |
| 11/13/21 | Kidera Gymnasium - Nazareth College | Rensselaer 61, Nazareth 60 | Box score |
| 11/12/21 | Kidera Gymnasium - Nazareth College | Nazareth 80, Cazenovia 72 | Box score |
| 11/09/21 | Kidera Gymnasium - Nazareth College | Nazareth 70, Buffalo State 65 | Box score |